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IDEXX Chlamydiosis Total Ab Test

Chlamydiosis/Chlamydophila abortus

The IDEXX Chlamydiosis Total Ab Test is an enzyme immunoassay for the detection of antibodies against Chlamydophila abortus in serum and plasma of ruminants.

The IDEXX Chlamydiosis Total Ab Test includes chemical reagents (wash, substrate, stop solutions) that can also be used with IDEXX kits that test for other abortive diseases (B. abortus, neosporosis, toxoplasmosis, Q fever).

* Availability / Distribution: Outside the U.S.

Test details

Features

Serum and plasma samples of ruminants
Results within 2.5 hours
Adapted to automation (bovine, caprine, ovine)

Part numbers and sizes

CLA1135T (2 plates/strips)

About Chlamydiosis/Chlamydophila abortus

Chlamydophila abortus, formerly known as Chlamydia psittaci immunotype 1, is the causative agent of ovine chlamydiosis (enzootic abortion). The disease primarily affects sheep and goats and less commonly, cattle and deer. C. abortus causes considerable reproductive losses worldwide, particularly in areas where flocks are kept closely congregated during lambing season.

Chlamydophila-infected animals show no clinical illness prior to abortion. Pathogenesis commences when chlamydial invasion of placentomes produces a progressively diffuse inflammatory response and tissue necrosis. Some animals may shed Chlamydophila spp. in vaginal fluids for more than two weeks before abortion and up to more than two weeks after abortion. This may explain the higher incidence of abortion in newly infected herds, since the susceptibility to infection varies in relation to the physiological status of the animal.

The success of eradication and surveillance programs depends on the quality and the effectiveness of available diagnostic tools. The isolation of the microorganism is difficult and the diagnosis is mainly based on serological methods as agent isolation remains a difficult and time-consuming task.

For this reason, the ELISA is easy to implement, and the analysis of small numbers of samples, as well as largescale screening, is facilitated with this method.